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Peptides are usually well tolerated at micro-doses, but any bioactive compound can cause reactions

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Side effect rates at 12mg are meaningfully higher than at 8mg: Nausea: 43.2% of participants (vs 38.1% at 9mg) Diarrhea: 33.1% (vs 34.7% at 9mg) Constipation: 25.0% (vs 21.8% at 9mg) Vomiting: 20.9% (vs 20.4% at 9mg) The decision between 8mg, 10mg, and 12mg as a maintenance dose should be made based on individual response

We do not recommend it for anyone who is pregnant, has active cancer, or has serious liver or kidney issues, since those conditions may interfere with how the body processes NAD

Half-Life The medication has a half-life of approximately 12 hours, meaning your body eliminates half of the drug every 12 hours