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Constipation is a common side effect of weight management and diabetes medications like semaglutide (Wegovy) and tirzepatide (Mounjaro)

Since none of the GLP-1RA are approved in pregnancy, a cohort study approved the potency of liraglutide, in early pregnancy, despite its adverse outcomes such as preterm birth, preeclampsia and gestational diabetes mellitus (GDM) (90)

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Effects of glucagon-like peptide-1 analog liraglutide on the systemic inflammation in high-fat-diet-induced mice

Stimulating -cell regeneration by combining a GPR119 agonist with a DPP-IV inhibitor