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EZH2 represses IGFBP1 (a decidualization marker) by increasing H3K27Me3 at the IGFBP1 promoter, impairing decidualization, while EZH2 knockdown or conditional deletion in mouse ESCs rescues decidualization defects and improves fertility ( Chromatin remodeling factors also play a pivotal role

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Gut Microbiota Dysbiosis Accelerates Prostate Cancer Progression Through Increased LPCAT1 Expression and Enhanced DNA Repair Pathways

Available from: [DOI] [PMC free article] [PubMed] Jadouali SM, Atifi H, Mamouni R, Majourhat K, Bouzouba Z, Laknifli A, et al

2019), among which glutathione synthase (GSS) catalyzes the synthesis of reduced glutathione from -glutamylcysteine and glycine in an ATP-dependent manner (Njalsson et al